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CD45RO 抗体 (Biotin)

This anti-CD45RO antibody is a 小鼠 单克隆 antibody detecting CD45RO in FACS. Suitable for 人.
产品编号 ABIN2661094
发货至: 中国

Quick Overview for CD45RO 抗体 (Biotin) (ABIN2661094)

抗原

CD45RO

适用

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宿主

  • 66
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小鼠

克隆类型

  • 67
  • 12
单克隆

标记

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This CD45RO antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

UCHL1
  • 交叉反应

    Chimpanzee, Marmoset

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD45RO

    别名

    CD45RO

    背景

    CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
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